Kelley DR, Reshef YA. Sequential regulatory activity prediction across chromosomes with convolutional neural networks. bioRxiv 10.1101/161851 (2017). [link]

Reshef YA, Finucane HK, Kelley DR, Gusev A, Kotliar D, Ulirsch JC, Hormozdiari F, O'Connor L, Geijn B, Loh P, Grossman S, Bhatia G, Gazal S, Palamara PF, Pinello L, Patterson N, Adams R, Price A. Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk. bioRxiv 10.1101/204685 (2017) [link]

Delas MJ, Sabin LR, Dolzhenko E, Knott SR, MAravilla EM, Jackson BT, Wild SA, Kovacevic T, Stork EM, Zhou M, Erard N, Lee E, Kelley DR, Roth M, Barbosa IA, Zuber J, Rinn JL, Smith AD, Hannon GJ. lncRNA requirements for mouse acute myeloid leukemia and normal differentiation. eLIFE (2017). [link]

Feigin ME, Garvin T, Bailey P, Waddell N, Chang DK, Kelley DR, Shuai S, Gallinger S, McPherson JD, Grimmond SM, Khurana E, Stein LD, Blankin AV, Schatz MC, Tuveson DA. Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma. Nature Genetics 49(6) (2017). [link]


Kelley DR, Snoek J, Rinn JL. Basset: Learning the regulatory code of the accessible genome with deep convolutional neural networks. Genome Research 26:7 (2016). [link]

Hendrickson D*, Kelley DR*, Tenen D, Bernstein, B., Rinn JL. Widespread RNA binding by chromatin-associated proteins. Genome Biology 17:28 (2016). [link]


Kelley DR, Hendrickson D, Tenen D, Rinn JL. Transposable elements modulate human RNA abundance and splicing via specific RNA-protein interactions. Genome Biology 15:537 (2014). [link]

Hacisuleyman E, Goff L, Trapnell C, Williams A, Henao-Mejia J, Sun L, McClanahan P, Hendrickson DG, Sauvageau M, Kelley DR, Morse M, Engreitz J, Lander ES, Guttman M, Lodish HF, Flavell R, Raj A, Rinn JL. Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre. Nat Struct Mol Biol (2014). [link]


Gifford C, Ziller MJ, Gu H, Trapnell C, Donaghey J, Tsankov A, Shalek AK, Kelley DR, Shishkin AA, Issner R, Zhang X, Coyne M, Fostel JL, Holmes L, Meldrim J, Guttman M, Epstein C, Park H, Kohlbacher O, Rinn J, Gnirke A, Lander ES, Bernstein BE, Meissner A. Transcriptional and epigenetic dynamics during specification of human embryonic stem cells. Cell 153:5 (2013). [link]

Sun L, Goff L, Trapnell C, Alexander R, Lo KA, Hacisuleyman E, Sauvageau M, Tazon-Vega B, Kelley DR, Hendrickson DG, Yuan B, Kellis M, Lodish HF, Rinn JL. Long noncoding RNAs regulate adipogenesis. Proc Natl Acad Sci 110:9 (2013). [link]


Kelley DR, Rinn JL. Transposable elements reveal a stem cell specific class of long noncoding RNA. Genome Biology 13:R107 (2012). [link]

Zimin AV, Kelley DR, Roberts M, Marcais G, Salzberg SL, Yorke JA. Mis-Assembled “Segmental Duplications” in Two Versions of the Bos taurus Genome. PLoS One 7:8 (2012). [link]

Trapnell C, Roberts A, Goff L, Pertea G, Kim D, Kelley DR, Pimentel H, Salzberg SL, Rinn JL, Pachter L. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks. Nature Protocols 7:3 (2012). [link]

Kelley DR, Liu B, Delcher A, Pop M, Salzberg SL. Gene prediction with Glimmer for metagenomic sequences augmented by classification and clustering. Nucleic Acids Research 40:1 e9 (2012). [link]


Earl D, … [71 authors]. Assemblathon 1: A competitive assessment of de novo short read assembly methods. Genome Research 21:12 (2011). [link]

Kelley DR, Kingsford C. Extracting between-pathway models from E-MAP interactions using expected graph compression. Journal of Computational Biology 18:3 (2011). [link]


Kelley DR, Schatz MC, Salzberg SL. Quake: quality-aware error correction of sequencing reads. Genome Biology 11:R116 (2010). [link]

Kelley DR, Salzberg SL. Clustering metagenomic sequences with interpolated Markov models. BMC Bioinformatics 11:544 (2010). [link]

Kelley DR, Salzberg SL. Detection and correction of false segmental duplications caused by mis-assembly. Genome Biology 11:R28 (2010). [link]


Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Marcais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL. A whole-genome assembly of the domestic cow, Bos Taurus. Genome Biology 10:R42 (2009). [link]

Salzberg SL, … [35 authors]. Genome sequence and rapid evolution of the rice pathogen Xanthomonas oryzae pv. oryzae PX099A. BMC Genomics 9:204 (2008). [link]